Effectiveness of Simvastatin Versus Gemfibrozil for Primary Prevention of Cardiovascular Events: A Retrospective Cohort Study of 223,699 Primary Care Patients.
Joseph Edgar BlaisXuxiao YeEric Yuk Fai WanWilliam Chi Wai WongIan Chi Kei Ck WongChristopher Wai Kei LamEsther Wai Yin ChanPublished in: Clinical drug investigation (2022)
The results of this study showed better population-level effectiveness of simvastatin compared with gemfibrozil for the primary prevention of MACE; however, a definitive randomized controlled trial is required to compare simvastatin with gemfibrozil among patients with low HDL cholesterol, as they appear to obtain benefit with gemfibrozil.
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