Blocking hepatocarcinogenesis by a cytochrome P450 family member with female-preferential expression.

Fubo JiJianjuan ZhangNiya LiuYuanzhuo GuYan ZhangPeipei HuangNachuan ZhangShengda LinRan PanZhuoxian MengXin-Hua FengStephanie RoesslerXin ZhengJunfang Ji

Published in: Gut (2022)

The liver-specific CYP39A1 with female-preferential expression was a strong suppressor of HCC development. Strategies to up-regulate CYP39A1 might be promising methods for HCC treatment in both women and men in future.

Keyphrases

poor prognosis
polycystic ovary syndrome
long non coding rna
adipose tissue
pregnancy outcomes
combination therapy
cervical cancer screening
replacement therapy