Energy Balance and Bone Health: a Nutrient Availability Perspective.
Beatriz BermudezToru IshiiYuan-Haw WuR Dana CarpenterVanessa D SherkPublished in: Current osteoporosis reports (2022)
The skeleton is a primary site for fatty acid and glucose uptake. The trafficking of carbohydrates and fats into tissues changes with weight loss and periods of weight gain. Exercise acutely influences nutrient uptake into bone and may affect nutrient partitioning to bone. Bone cells secrete hormones that signal to the brain and other tissues information about its energetic state, which may alter whole-body nutrient trafficking. There is a critical need for studies to address the changes that metabolic perturbations have on nutrient availability in bone.
Keyphrases
- bone mineral density
- weight gain
- weight loss
- soft tissue
- bone loss
- bone regeneration
- gene expression
- postmenopausal women
- public health
- body mass index
- fatty acid
- healthcare
- bariatric surgery
- induced apoptosis
- cell death
- type diabetes
- health information
- oxidative stress
- cell proliferation
- resting state
- blood glucose
- insulin resistance
- functional connectivity
- cerebral ischemia
- subarachnoid hemorrhage
- glycemic control
- obese patients