Comparison of commercial 5-aminolevulinic acid (Gliolan®) and the pharmacy-compounded solution fluorescence in glioblastoma.

Santiago Garfias-ArjonaMónica Lara AlmuniaJavier Ángel Ibáñez DomínguezOlga Delgado SánchezPriam VillalongaRuth Villalonga-PlanellsJavier Pierola LopeteguiJoan Bestard EscalasAlbert Maimó BarcelóMarta Brell Doval

Published in: Acta neurochirurgica (2019)

Both, compounded and commercial 5-ALA preparations produce equivalent fluorescent responses in human glioblastoma cells. Fluorescence intensity is cell line specific, but fluorescent properties of both preparations are undistinguishable.

Keyphrases

quantum dots
living cells
single molecule
induced apoptosis
energy transfer
endothelial cells
photodynamic therapy
cell cycle arrest
induced pluripotent stem cells
high intensity
fluorescent probe
signaling pathway
pluripotent stem cells
oxidative stress