Is There a Benefit of Oxaliplatin in Combination with Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal Cancer? An Updated Meta-Analysis.

Gaëtan Des GuetzThierry LandreMarc A BolletMuriel Mathonnet Laurent Quéro

Published in: Cancers (2021)

Our meta-analysis with long-term results from the randomized studies showed a benefit of the addition of OXP + 5FU regiment in terms of DFS, metastatic progression, and pCR rate that did not translate to improved OS.

Keyphrases

rectal cancer
systematic review
locally advanced
case control
meta analyses
squamous cell carcinoma
small cell lung cancer
double blind
open label
lymph node
randomized controlled trial
phase iii