Exploring the immunogenicity of non-canonical HLA-I tumor ligands identified through proteogenomics.
Maria Lozano-RabellaAndrea García-GarijoJara PalomeroAnna Yuste-EstevanezFlorian ErhardJuan Martín-LiberalMaria Ochoa de OlzaIgnacio MatosJared J GartnerMichael GhoshFrancesc CanalsAugust Vidal BelJosep Maria PiulatsXavier M GuiuIrene BranaEva Muñoz CouseloElena GarraldaAndreas SchlosserAlena GrosPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Our findings predict a limited contribution of nonC-TL to cancer immunosurveillance but demonstrate they may be attractive novel targets for widely applicable immunotherapies.