Somatostatin receptor subtype 2A expression and genetics in 184 paragangliomas: a single center retrospective observational study.

Yanting ShenYu LuoMinghao LiRongkui LuoLingli ChenXin GaoJingjing JiangYujun LiuZhiqiang LuJing Zhang

Published in: Endocrine (2024)

SSTR2A negativity was correlated with extra-adrenal tumor location and PVs in cluster 1B and cluster 2 genes such as VHL, FGFR1 and HRAS. Immunohistochemistry of SSTR2A should be taken into consideration in the personalized management of PGLs.

Keyphrases

poor prognosis
binding protein
genome wide
gene expression
genome wide identification