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Nintedanib in patients with systemic sclerosis-associated interstitial lung disease: subgroup analyses by autoantibody status and skin score.

Masataka KuwanaYannick AllanoreChristopher P DentonJörg Hw DistlerVirginia SteenZsuzsanna H McMahanMarco Matucci-CerinicMaureen D MayesElizabeth R VolkmannCorinna MiedeMartina GahlemannManuel Quaresma LicMargarida AlvesAnastasiia Kozlova
Published in: Arthritis & rheumatology (Hoboken, N.J.) (2021)
In patients with SSc-ILD, no heterogeneity was detected in the treatment effect of nintedanib in reducing the annual rate of decline in FVC across subgroups based on ATA status, mRSS, and SSc subtype.
Keyphrases
  • interstitial lung disease
  • systemic sclerosis
  • idiopathic pulmonary fibrosis
  • rheumatoid arthritis
  • single cell
  • soft tissue
  • randomized controlled trial
  • wound healing
  • phase iii
  • study protocol
  • combination therapy