Modelling of the relationship between infliximab exposure, faecal calprotectin and endoscopic remission in patients with Crohn's disease.

Erwin DreesenSophie BerendsDavid LaharieGeert D'HaensSeverine VermeireAnn GilsRon Mathôt
Published in: British journal of clinical pharmacology (2020)
Model-informed infliximab dose optimisation towards a predefined fCal concentration (while accounting for PK and PD variability) may improve effectiveness of infliximab therapy.