Real-world Trends, Rural-urban Differences, and Socioeconomic Disparities in Utilization of Narrow versus Broad Next-generation Sequencing Panels.
Yiqing ZhaoAnastasios DimouZachary C FogartyJun JiangHongfang LiuWilliam Bruce WongChen WangPublished in: Cancer research communications (2024)
We identified socioeconomic and rurality disparities in the use of genomic tests and trial matching by panel size, which may have implications for equal access to targeted therapies. The lack of association between large panel tests and clinical trial matching by socioeconomic status, suggests a potential health equity impact, while removing barriers in access to large panels for rural patients may improve access to trials. However, further research is needed.
Keyphrases
- clinical trial
- end stage renal disease
- south africa
- ejection fraction
- study protocol
- public health
- healthcare
- newly diagnosed
- chronic kidney disease
- phase ii
- phase iii
- copy number
- mental health
- peritoneal dialysis
- prognostic factors
- randomized controlled trial
- gene expression
- patient reported outcomes
- climate change
- social media
- affordable care act
- health promotion