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Radiation therapy for ventricular arrhythmias.

Xingzhou LiuluPoornima BalajiJeffrey BarberKasun De SilvaTiarne MurrayAndrew HickeyTimothy G CampbellJillian HarrisHarriet E GeeVerity AhernSaurabh KumarEric HauPierre C Qian
Published in: Journal of medical imaging and radiation oncology (2024)
Ventricular arrhythmias (VA) can be life-threatening arrhythmias that result in significant morbidity and mortality. Catheter ablation (CA) is an invasive treatment modality that can be effective in the treatment of VA where medications fail. Recurrence occurs commonly following CA due to an inability to deliver lesions of adequate depth to cauterise the electrical circuits that drive VA or reach areas of scar responsible for VA. Stereotactic body radiotherapy is a non-invasive treatment modality that allows volumetric delivery of energy to treat circuits that cannot be reached by CA. It overcomes the weaknesses of CA and has been successfully utilised in small clinical trials to treat refractory VA. This article summarises the current evidence for this novel treatment modality and the steps that will be required to bring it to the forefront of VA treatment.
Keyphrases
  • clinical trial
  • heart failure
  • randomized controlled trial
  • radiation therapy
  • left ventricular
  • optical coherence tomography
  • left atrial appendage
  • rectal cancer
  • radiation induced