Single-cell RNA sequencing reveals markers of disease progression in primary cutaneous T-cell lymphoma.

Katharina RindlerConstanze JonakNatalia AlkonFelix M ThalerHarald KurzLisa E ShawGeorg StinglWolfgang WeningerFlorian HalbritterWolfgang M BauerMatthias FarlikPatrick M Brunner

Published in: Molecular cancer (2021)

Our data reveal a specific panel of biomarkers that might be used for monitoring MF disease progression. Altered expression of these genes may underlie the switch in clinical phenotype observed in advanced-stage MF.

Keyphrases

single cell
rna seq
poor prognosis
high throughput
genome wide
electronic health record
big data
binding protein
bioinformatics analysis
machine learning
long non coding rna
transcription factor
artificial intelligence