Expression of factor XIII originating from synovial fibroblasts and macrophages induced by interleukin-6 signaling.

Hirofumi WatanabeSho MokudaTadahiro TokunagaHiroki KohnoMichinori IshitokuKei ArakiTomohiro SugimotoYusuke YoshidaToshihiro YamamotoMayuko MatsumotoJunya MasumotoShintaro HirataEiji Sugiyama

Published in: Inflammation and regeneration (2023)

Our findings highlight that synovial tissue is one of the sources of FXIII production. We also have demonstrated IL-6-dependent FXIII-A expression and the novel potential functions of FXIII-B.

Keyphrases

poor prognosis
binding protein
long non coding rna
extracellular matrix
climate change