Dose-related cardiac outcomes in response to postnatal dexamethasone treatment in premature lambs.
Amanda VrseljaJennifer Jane PillowJonathan G BensleySiavash Ahmadi-NoorbakhshPeter B NobleMary Jane BlackPublished in: Anatomical record (Hoboken, N.J. : 2007) (2023)
Neonatal dexamethasone treatment led to adverse effects in the preterm heart in a dose-dependent manner within the first week of life. The observed cardiac changes associated with high-dose postnatal dexamethasone treatment may influence postnatal growth and remodeling of the preterm heart and subsequent long-term cardiac function.