Extent of and Reasons for Discontinuation and Nonpublication of Interventional Trials on Connective Tissue Diseases: An Observational Study.

Alejandro BriganteBarbara RussoDenis MonginKim LauperDanièle AllaliDelphine Sophie Courvoisier Michele Iudici

Published in: Arthritis care & research (2022)

One of 3 registered RCTs on CTDs fails to be completed or published. This represents a waste of resources and raises ethical concerns regarding hidden clinical data and unfruitful participation by patients.

Keyphrases

end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
physical activity
prognostic factors
peritoneal dialysis
randomized controlled trial
heavy metals
systematic review
electronic health record
big data
risk assessment
decision making
sewage sludge
patient reported
meta analyses