Angiogenic desmoplastic histopathological growth pattern as a prognostic marker of good outcome in patients with colorectal liver metastases.
Boris GaljartPieter M H NieropEric P van der StokRobert R J Coebergh van den BraakDiederik J HöppenerSofie DaelemansLuc Y DirixCornelis VerhoefPeter B VermeulenDirk J van GrünhagenPublished in: Angiogenesis (2019)
The current study demonstrates that the angiogenic dHGP in CRLM resected from chemo-naive patients acts as a strong, positive prognostic marker, unmatched by any other prognosticator. This observation warrants the evaluation of the clinical utility of HGPs in prospective clinical trials.