Co-exposure to Toluene and Noise Made Synergistic and Antagonistic Effects on Some Neurotoxic Parameters in New Zealand White Rabbits.

The brain tissue can be adversely affected by various agents, including noise and toluene. This study aimed to examine the effects of simultaneous exposure to noise and toluene on the nervous system. Twenty-four healthy male white New Zealand rabbits were randomly divided into four groups: control, noise, toluene, and simultaneous exposure to noise and toluene. The study involved a two-week in-vivo experiment, subjecting the rabbits to 100 dB noise and 1000 ppm toluene for eight hours per day. This study showed that exposure to noise and toluene changed different parameters relating to the neurological system. Furthermore, noise and toluene induced some adverse effects on the brain tissue. This study suggested that exposure to noise and toluene can lead to harmful effects on the brain tissue, posing a significant risk to the neurological system.