The Impact of HIV Upon the PCI Results: A Systematic Review and Meta-Analysis.
Amr Ehab El-QushayriMohammad Rashidul HashanMd Mahfuj AlamMuhammad Sanowar KhanNasser G AlqahtaniPublished in: Reviews in medical virology (2024)
The aim of this systematic review and meta-analysis was to comprehensively evaluate the latest evidences and summarise the impact of HIV on PCI outcomes. A PRISMA guided literature search was conducted on 14 February 2024 in Web of Science, PubMed, Virtual Health Library, Google Scholar and Scopus. We searched with the term '("percutaneous coronary intervention" OR "PCI") AND ("human immunodeficiency virus" OR "HIV" OR "acquired immunodeficiency syndrome" OR "AIDS")' after selecting the keywords from randomly chosen included papers. We included 8 papers of 781 screened records. HIV (+) patients had significant in-hospital, 1-year and overall (event at the last follow up point) all-cause mortality compared to HIV (-) group (OR: 1.73, 95%CI: 1.57-1.90, p < 0.01), (OR: 1.39, 95%CI: 1.07-1.81, p = 0.01) and (OR: 1.69, 95%CI: 1.55-1.85, p < 0.01), respectively. HIV (+) patients had significantly higher odds of developing MACE (OR: 1.35, 95%CI: 1.12-1.62, p = 0.001) compared to the HIV (-) group. No differences between both groups were detected regarding in-hospital and overall CV mortality, TVR, TLR, post-PCI TIMI grade 3 flow, cerebrovascular accidents and recurrent coronary events (p > 0.05). Our study revealed that people with HIV who underwent PCI in this modern era may have worse short and long-term PCI outcomes. This finding highlights the need for specialised cardiovascular care protocols for the HIV population. However, enhanced clinical management and preventative measures are imperative to improve PCI success rates in patients with HIV.
Keyphrases
- human immunodeficiency virus
- antiretroviral therapy
- hiv positive
- hiv infected
- hiv testing
- percutaneous coronary intervention
- hepatitis c virus
- hiv aids
- coronary artery disease
- men who have sex with men
- acute coronary syndrome
- acute myocardial infarction
- st segment elevation myocardial infarction
- antiplatelet therapy
- st elevation myocardial infarction
- healthcare
- end stage renal disease
- systematic review
- chronic kidney disease
- atrial fibrillation
- randomized controlled trial
- public health
- coronary artery bypass grafting
- coronary artery
- south africa
- type diabetes
- adipose tissue
- skeletal muscle
- ejection fraction
- cardiovascular disease
- single cell
- preterm infants
- transcatheter aortic valve replacement
- drug induced
- health information
- preterm birth
- aortic stenosis