A practical method for oral administration of isotretinoin in pediatric oncology patient: A case study of neuroblastoma.
Abdulrahman M AlwhaibiMiteb AlenaziBana AlmadiAbdulaziz AlotaibiSultan M AlshehriFaiyaz ShakeelPublished in: Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners (2022)
To the best of our knowledge, this is the first report that suggests a practical method for administering isotretinoin in liquid form, particularly in pediatric oncology patients. Isotretinoin was noted to be stable in olive oil and its exposure to light and oxygen would not be an issue given the short time from preparation to administration and the low emphasis on exposure by the manufacturer when such a method is recommended.