Expression of Toll-like receptors 2 and 4 in the saliva of patients with systemic lupus erythematosus and chronic periodontitis.
Consuelo P C MarquesVandilson Pinheiro RodriguesLarissa C de CarvalhoLouise P NichilattiMayra M FrancoFernando José B PatrícioMarcelo MagalhãesMarcelo S de AndradeBruno B BenattiPublished in: Clinical rheumatology (2021)
Reduced TRL 2 and 4 expression in saliva was associated with the presence of CP in SLE patients. Key Points • Patients affected by isolated CP or SLE had higher TLR2 and TLR4 expression. • TLR under-expression may be associated with a worse periodontal status in SLE. • Abnormalities in TLRs expression may increase the susceptibility to periodontitis.