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Individualized regimen of low-dose rituximab monotherapy for new-onset AChR-positive generalized myasthenia gravis.

Ying DuChuan LiYun-Feng HaoChao ZhaoQi YanDan YaoLin LiWei Zhang
Published in: Journal of neurology (2022)
Our study firstly showed that individualized regimen of low-dose RTX monotherapy is effective and safe for early treatment of new-onset generalized AChR-MG, and practicable for directing RTX reinfusion and withdrawal. Moreover, the monotherapy protocol was also indicated to be extensively applicable in both new-onset AChR-MG with thymoma (thymectomy) and without thymoma.
Keyphrases
  • myasthenia gravis
  • low dose
  • combination therapy
  • open label
  • high dose
  • randomized controlled trial
  • multidrug resistant
  • diffuse large b cell lymphoma
  • cell free
  • clinical trial
  • replacement therapy
  • smoking cessation