Intestinal histological findings in patients with spondyloarthritis: a study on the relationship with disease activity.
Juliana SimioniThelma SkareSergio IoshiiAna CamposBetania LongoIara Messias-ReasonRenato Mitsunori NisiharaPublished in: Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva (2022)
The role of intestinal microbioma and subclinical bowel inflammation in the etiology of sponsyloarthritis (SpA) has gained a lot of attention recently. Almost 65% of SpA patients will have asymptomatic bowel inflammation if assessed by ileocolonoscopy. The connection between intestinal inflammation and SpA originated the gut-joint axis hypothesis in which monocytes and T cells found in the joint would have origin in the gut.