The effect of weight loss on whole-body and tissue-specific insulin sensitivity and hepatic lipid content and composition: SWEET substudy.
Michelle D PangJacco J A J BastingsYvonne M H Op den Kamp-BrulsJoanne Allison HarroldLouise KjølbaekJason C G HalfordTanja C M AdamAnne RabenVera B Schrauwen-HinderlingGijs H GoossensEllen E BlaakPublished in: Obesity (Silver Spring, Md.) (2023)
Weight loss decreased IHL content and the hepatic saturated fatty acid fraction. The decrease in IHL content was associated with weight-loss-induced improvement in hepatic insulin sensitivity in individuals with overweight or obesity.