Identification and characterization of select oxysterols as ligands for GPR17.
Anthony W HarringtonChanglu LiuNaomi PhillipsDiane NepomucenoChester KueiJoseph ChangWeixuan ChenSteven W SuttonDaniel O'MalleyLy PhamXiang YaoSiquan SunPascal BonaventurePublished in: British journal of pharmacology (2022)
Oxysterols, including but not limited to 24S-HC, could be physiological activators for GPR17 and thus potentially regulate OPC differentiation and myelination through activation of the receptor.
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