TB-Molecular Bacterial Load Assay reveals early delayed bacterial killing in relapse patients.

Nyanda Elias NtinginyaAbishek BakuliDaniel MapambaWilber SabiitiGibson KibikiLilian Tina MinjaDavis KuchakaKlaus ReitherPatrick Peter John PhillipsMartin Johan BoereeStephen H GillespieMichael HoelscherNorbert Heinrich

Published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2022)

Bacterial killing in TB-patients with relapse was compared to patients achieving cure, measured by TB-molecular bacterial load assay(TB-MBLA) or MGIT time to positivity(TTP). TB-MBLA in 4 relapsed patients was significantly different compared to 132 cured patients after 2 weeks of treatment; MGIT TTP showed a significant difference from week 8.

Keyphrases

end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
mycobacterium tuberculosis
peritoneal dialysis
randomized controlled trial
clinical trial
acute myeloid leukemia
patient reported outcomes
hodgkin lymphoma
combination therapy
gestational age