Characterization of the Synergistic Effect between Ligands of Opioid and Free Fatty Acid Receptors in the Mouse Model of Colitis.

Agata Binienda Adam Makaro Marcin TalarJulia B KrajewskaAleksandra TarasiukAdrian BartoszekAdam FabisiakPaula MosińskaKarolina NiewinnaKatarzyna DziedziczakMikołaj ŚwierczyńskiRadzisław KordekMaciej Salaga Jakub Fichna

Published in: Molecules (Basel, Switzerland) (2021)

Treatment with ligands of ORs and FFARs may affect the immune cells in the inflammation; however, no significant influence on the severity of colitis and no synergistic effect were observed.

Keyphrases

mouse model
fatty acid
oxidative stress
chronic pain
pain management
ulcerative colitis
replacement therapy