Circulating exosome long non-coding RNAs are associated with atrial structural remodeling by increasing systemic inflammation in atrial fibrillation patients.
Yue YuanXuejie HanXinbo ZhaoHaiyu ZhangAsiia VinogradXin BiXiaoxu DuanYukai CaoQiang GaoJia SongYue LiYue LiPublished in: Journal of translational internal medicine (2024)
Our study provides the transcriptome profile revealing pattern of circulating exosome lncRNAs in atrial structural remodeling, which bring valuable insights into improving prognosis and therapeutic targets for AF.
Keyphrases
- atrial fibrillation
- long non coding rna
- catheter ablation
- left atrial
- end stage renal disease
- oral anticoagulants
- chronic kidney disease
- ejection fraction
- poor prognosis
- newly diagnosed
- left atrial appendage
- heart failure
- direct oral anticoagulants
- gene expression
- prognostic factors
- percutaneous coronary intervention
- genome wide
- peritoneal dialysis
- rna seq
- single cell
- patient reported outcomes