Simple blood tests to diagnose compensated advanced chronic liver disease and stratify the risk of clinically significant portal hypertension.

Georg Semmler Lukas Hartl Yuly Paulin Mendoza Benedikt Simbrunner Mathias Jachs Lorenz Balcar Michael Schwarz Benedikt Silvester Hofer Laurenz FritzAnna SchedlbauerKatharina StopferDaniela NeumayerJurij MaurerRobin SzymanskiElias Laurin MeyerBernhard Scheiner Peter Quehenberger Michael TraunerElmar AignerAnnalisa Berzigotti Thomas Reiberger Mattias Mandorfer

Published in: Hepatology (Baltimore, Md.) (2024)

Simple, broadly available laboratory tests (FIB-4/VITRO) facilitate cACLD detection and CSPH risk stratification in patients with (suspected) liver disease. This blood-based approach is applicable outside of specialized clinics and may promote early intervention.

Keyphrases

blood pressure
randomized controlled trial
primary care
loop mediated isothermal amplification
liver fibrosis
drug induced