Brown Adipocyte ADRB3 Mediates Cardioprotection via Suppressing Exosomal iNOS.

Jing-Rong LinLi-Li-Qiang DingLian XuJun HuangZe-Bei ZhangXiao-Hui ChenYu-Wen ChengCheng-Chao RuanPing-Jin Gao

Published in: Circulation research (2022)

Our data illustrated a new endocrine pattern of BAT in regulating cardiac remodeling, suggesting that activation of ADRB3 in brown adipocytes offers cardiac protection through suppressing exosomal iNOS.

Keyphrases

nitric oxide synthase
adipose tissue
left ventricular
signaling pathway
electronic health record
big data
fatty acid
type diabetes
heart failure
metabolic syndrome
artificial intelligence
data analysis