Digital quantitation of bridging fibrosis and septa reveals changes in natural history and treatment not seen with conventional histology.

Nikolai V Naoumov David E KleinerElaine ChngDominique BreesChandrassegar SaravananYayun RenDean TaiArun J Sanyal

Published in: Liver international : official journal of the International Association for the Study of the Liver (2024)

SHG/TPEF microscopy with AI provides greater granularity and precision in assessing fibrosis dynamics in patients with bridging fibrosis, thus advancing knowledge development of fibrosis evolution in natural history and in clinical trials.

Keyphrases

clinical trial
healthcare
liver fibrosis
mass spectrometry
high resolution
ms ms
randomized controlled trial
single molecule
machine learning
optical coherence tomography
liquid chromatography tandem mass spectrometry
high speed
phase ii
label free
smoking cessation
solid phase extraction