Cost effectiveness of intermittent screening followed by treatment versus intermittent preventive treatment during pregnancy in West Africa: analysis and modelling of results from a non-inferiority trial.

Silke FernandesElisa SicuriDiawara HalimatouJames AkaziliKalifa BoiangDaniel ChandramohanSheikh CoulibalySory Ibrahim DiawaraKassoum KayentaoFeiko Ter KuilePascal MagnussenHarry TagborJohn WilliamsArouna WoukeuMatthew CairnsBrian GreenwoodKara Hanson

Published in: Malaria journal (2016)

At SP efficacy levels currently observed in the trial settings it would not be cost-effective to switch from IPTp-SP to ISTp-AL, mainly due to the substantially higher costs of ISTp-AL and limited difference in outcomes. The modelling results indicate thresholds below which IPT-SP efficacy must fall for ISTp-AL to become a cost-effective option for the prevention of malaria in pregnancy.

Keyphrases

clinical trial
study protocol
phase iii
phase ii
type diabetes
randomized controlled trial
metabolic syndrome
adipose tissue
open label
preterm birth
data analysis