PDZ Binding Kinase/T-LAK Cell-Derived Protein Kinase Plays an Oncogenic Role and Promotes Immune Escape in Human Tumors.

Tingting Feng Yan Zhang Sunbin Ling Chenyang Xu Yingqi Lyu Tingting Lu Xinyuan Liu Lisha Ying Yafeng Wan Haijun Zhong Dan Su

Published in: Journal of oncology (2021)

PBK may play an oncogenic role in most solid tumors and promotes immune escape, especially in KIRC, LGG, and LIHC. This study suggests the potential value of PBK inhibitors combined with immunotherapy.

Keyphrases

protein kinase
endothelial cells
transcription factor
human health
pluripotent stem cells