Rational engineering of Streptomyces albus J1074 for the overexpression of secondary metabolite gene clusters.

Dimitris KallifidasGuangde JiangYousong DingHendrik Luesch

Published in: Microbial cell factories (2018)

Rational engineering of Streptomyces albus J1074 yielded a series of mutants with improved capabilities for native and heterologous expression of secondary metabolite gene clusters.

Keyphrases

genome wide
copy number
poor prognosis
genome wide identification
transcription factor
dna methylation
binding protein
saccharomyces cerevisiae
long non coding rna