Epithelial-to-mesenchymal transition status of primary breast carcinomas and its correlation with metastatic behavior.
C Dilara Savci-HeijninkH HalfwerkG K J HooijerJ KosterH M HorlingsS L MeijerM J van de VijverPublished in: Breast cancer research and treatment (2019)
The EMT status of breast cancers, as defined by the presence of a core EMT gene expression signature is associated with non-basal-type tumors, but not with the pattern of distant metastasis. Of several potential immunohistochemical EMT markers, only NAT1 and TWIST1 expression levels were associated with the gene expression-based EMT status.