Breaking the Mucin Barrier: A New Affinity Chromatography-Mass Spectrometry Approach to Unveil Potential Cell Markers and Pathways Altered in Pseudomyxoma Peritonei.
Antonio Romero-RuizMelissa Granados-RodríguezFlorina I BuraFrancisca Valenzuela-MolinaBlanca Rufián-AndújarAna Martínez-LópezLidia Rodríguez-OrtizRosa Ortega-SalasMaría Torres-MartínezAna Moreno-SerranoJusto CastañoCarmen MichánJosé AlhamaMari C Vázquez-BorregoÁlvaro Arjona-SánchezPublished in: Biological procedures online (2024)
In sum, our results demonstrate that this protein isolation protocol from mucin will have a high impact, allowing the oncology research community to more rapidly advance in the knowledge of PMP and other mucinous neoplasms, as well as develop new and effective therapeutic strategies.
Keyphrases
- mass spectrometry
- liquid chromatography
- capillary electrophoresis
- healthcare
- high performance liquid chromatography
- single cell
- palliative care
- gas chromatography
- randomized controlled trial
- mental health
- low grade
- cell therapy
- tandem mass spectrometry
- high resolution
- high speed
- protein protein
- human health
- amino acid
- risk assessment
- high grade
- bone marrow