Growth arrest and DNA damage-inducible alpha regulates muscle repair and fat infiltration through ATP synthase F1 subunit alpha.
Wenjing YouShiqi LiuJianfei JiDefeng LingYuang TuYanbing ZhouWentao ChenTeresa G ValencakYizhen WangTizhong ShanPublished in: Journal of cachexia, sarcopenia and muscle (2022)
Our findings reveal a crucial role of GADD45A in regulating muscle repair and fat infiltration and suggest that inhibition of GADD45A by EGCG might be a potential strategy to combat fat infiltration and its associated muscle dysfunction.