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Hydroalcoholic Extract of Anchusa Italica Protects Global Cerebral Ischemia-Reperfusion Injury Via a Nitrergic Mechanism.

Samira AsgharzadeRobert D E SewellZahra RabieiFatemeh ForouzanfarSedigheh Kazemi SheikhshabaniMahmoud Rafieian-Kopaei
Published in: Basic and clinical neuroscience (2020)
The results indicated that the administration of HEAI even after the onset of ischemia protects the brain from free radical injury and inflammation via a down-regulation of iNOS expression inhibiting NO production and an up-regulation of BDNF mRNA.
Keyphrases
  • oxidative stress
  • ischemia reperfusion injury
  • poor prognosis
  • binding protein
  • signaling pathway
  • subarachnoid hemorrhage
  • cerebral ischemia
  • white matter
  • resting state
  • multiple sclerosis
  • brain injury