Rab32 connects ER stress to mitochondrial defects in multiple sclerosis.

Yohannes HaileXiaodan DengCarolina Ortiz-SandovalNasser TahbazAleksandra JanowiczJian-Qiang LuBradley J KerrNicholas J GutowskiJanet E HolleyPaul EggletonFabrizio GiulianiThomas Simmen

Published in: Journal of neuroinflammation (2017)

ER stress is strongly associated with Rab32 upregulation in the progression of MS, leading to mitochondrial dysfunction and neuronal death.

Keyphrases

multiple sclerosis
oxidative stress
white matter
poor prognosis
mass spectrometry
cell proliferation
signaling pathway
ms ms
brain injury