Olaparib plus Durvalumab, with or without Bevacizumab, as Treatment in PARP Inhibitor-Naïve Platinum-Sensitive Relapsed Ovarian Cancer: A Phase II Multi-Cohort Study.
Yvette DrewJae-Weon KimRichard T PensonDavid M O'MalleyChristine ParkinsonPatricia RoxburghRuth PlummerSeock-Ah ImMartina ImbimboMichelle FergusonOra RosengartenNeeltje SteeghsMin Hwan KimEinav Nili Gal-YamDaliah TsorefJae-Hoon KimBenoit YouMaja J A de JongeRoy I LalisangEelke H GortSara BastianKassondra MeyerLaura FeeneyNigel BakerMei-Lin Ah-SeeSusan M DomchekSusana BanerjeePublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Olaparib plus durvalumab continued to show notable clinical activity in women with gBRCAm PSROC. Olaparib plus durvalumab with bevacizumab demonstrated encouraging clinical activity in women with non-gBRCAm PSROC. No new safety signals were identified.