Neeltje Steeghs

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 62

Top Topics

Estrogen Receptor

Chronic Myeloid Leukemia

Small Cell Lung Cancer

Top Venues

Clinical cancer research : an official journal of the American Association for Cancer Research

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Nature medicine

Clinical pharmacokinetics

This page only lists publications with an associated author ORCID identifier.

Publications

Solange Peters, Eric Angevin, Teresa Alonso Gordoa, Kristoffer Staal Rohrberg, Ignacio Melero Bermejo, Begona Mellado, Jose-Luis Perez-Gracia, Josep Tabernero, Celine Adessi, Christophe Boetsch, Carl Watson, Joseph Dal Porto, David Dejardin, Christopher Del Nagro, Valeria Nicolini, Stefan Evers, Christiane Neumann, Barbara Leutgeb, Pavel Pisa, Eva Rossmann, José Saro, Pablo Umaña, Jehad Charo, Volker Teichgräber, Neeltje Steeghs
Obinutuzumab Pretreatment as a Novel Approach to Mitigate Formation of Anti-Drug Antibodies Against Cergutuzumab Amunaleukin in Patients with Solid Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (8) (2024)
Michael C Heinrich, Robin L Jones, Suzanne George, André B P van Kuilenburg, Patrick Schöffski, Margaret von Mehren, John R Zalcberg, Yoon-Koo Kang, Albiruni Abdul Razak, Jonathan Trent, Steven Attia, Axel Le Cesne, Brittany L Siontis, David Goldstein, Kjetil Boye, Cesar Sanchez, Neeltje Steeghs, Piotr Rutkowski, Mihaela Druta, Cesar Serrano, Neeta Somaiah, Ping Chi, William Reichmann, Kam Sprott, Haroun Achour, Matthew L Sherman, Rodrigo Ruiz-Soto, Jean Yves Blay, Sebastian Bauer
Ripretinib versus sunitinib in gastrointestinal stromal tumor: ctDNA biomarker analysis of the phase 3 INTRIGUE trial. Nature medicine 30 (2) (2024)
Neil H Segal, Ignacio Melero Bermejo, Victor Moreno, Neeltje Steeghs, Aurélien Marabelle, Kristoffer Staal Rohrberg, Maria E Rodriguez-Ruiz, Joseph P Eder, Cathy Eng, Gulam A Manji, Daniel Waterkamp, Barbara Leutgeb, Said Bouseida, Nick Flinn, Meghna Das Thakur, Markus C Elze, Hartmut Koeppen, Candice Jamois, Meret Martin-Facklam, Christopher H Lieu, Emiliano Calvo, Luis Paz-Ares, Josep Tabernero, Guillem Argilés
CEA-CD3 bispecific antibody cibisatamab with or without atezolizumab in patients with CEA-positive solid tumours: results of two multi-institutional Phase 1 trials. Nature communications 15 (1) (2024)
Marinda Meertens, Eline L Giraud, Maud B A van der Kleij, Kim Westerdijk, Niels A D Guchelaar, Roos F Bleckman, Amy Rieborn, Alex L T Imholz, Hans-Martin Otten, Annelie Vulink, Maartje Los, Paul Hamberg, Winette T A van der Graaf, Hans Gelderblom, Dirk Jan A R Moes, K Esther Broekman, Daan J Touw, Stijn L W Koolen, Ron H J Mathijssen, Alwin D R Huitema, Nielka P van Erp, Ingrid M E Desar, Neeltje Steeghs, null null
Evaluating the Clinical Impact and Feasibility of Therapeutic Drug Monitoring of Pazopanib in a Real-World Soft-Tissue Sarcoma Cohort. Clinical pharmacokinetics 63 (7) (2024)
Afshin Dowlati, Horst-Dieter Hummel, Stephane Champiat, Maria Eugenia Olmedo, Michael J Boyer, Kai He, Neeltje Steeghs, Hiroki Izumi, Melissa Lynne Johnson, Tatsuya Yoshida, Hasna Bouchaab, Hossein Borghaei, Enriqueta Felip Font, Philipp J Jost, Shirish M Gadgeel, Xi Chen, Youfei Yu, Pablo Martinez, Amanda Parkes, Luis G Paz-Ares
Sustained Clinical Benefit and Intracranial Activity of Tarlatamab in Previously Treated Small Cell Lung Cancer: DeLLphi-300 Trial Update. Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2024)
Deborah van de Wal, Dide den Hollander, Ingrid M E Desar, André B P van Kuilenburg, Astrid W Oosten, Anna K L Reyners, Neeltje Steeghs, Olga Husson, Winette T A van der Graaf
Financial difficulties experienced by patients with gastrointestinal stromal tumours (GIST) in the Netherlands: data from a cross-sectional multicentre study. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 32 (5) (2024)
Solange Peters, Eric Angevin, Teresa Alonso Gordoa, Kristoffer Staal Rohrberg, Ignacio Melero Bermejo, Begona Mellado, Jose-Luis Perez-Gracia, Josep Tabernero, Celine Adessi, Christophe Boetsch, Carl Watson, Joseph Dal Porto, David Dejardin, Christopher Del Nagro, Valeria Nicolini, Stefan Evers, Christiane Neumann, Barbara Leutgeb, Pavel Pisa, Eva Rossmann, José Saro, Pablo Umaña, Jehad Charo, Volker Teichgräber, Neeltje Steeghs
Obinutuzumab Pretreatment as a Novel Approach to Mitigate Formation of Anti-Drug Antibodies Against Cergutuzumab Amunaleukin in Patients with Solid Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Marinda Meertens, Eline L Giraud, Maud B A van der Kleij, Kim Westerdijk, Niels A D Guchelaar, Roos F Bleckman, Amy Rieborn, Alex L T Imholz, Hans-Martin Otten, Annelie Vulink, Maartje Los, Paul Hamberg, Winette T A van der Graaf, Hans Gelderblom, Dirk Jan A R Moes, K Esther Broekman, Daan J Touw, Stijn L W Koolen, Ron H J Mathijssen, Alwin D R Huitema, Nielka P van Erp, Ingrid M E Desar, Neeltje Steeghs, null null
Evaluating the Clinical Impact and Feasibility of Therapeutic Drug Monitoring of Pazopanib in a Real-World Soft-Tissue Sarcoma Cohort. Clinical pharmacokinetics 63 (7) (2024)
Alaa Embaby, Sanne C F A Huijberts, Liqin Wang, Rodrigo Leite de Oliveira, Hilde Rosing, Bastiaan Nuijen, Joyce Sanders, Ingrid Hofland, Charlaine van Steenis, Roelof J C Kluin, Cor Lieftink, Christopher G Smith, Christian U Blank, Johannes V van Thienen, John B A G Haanen, Neeltje Steeghs, Frans L Opdam, Jos H Beijnen, Alwin D R Huitema, René Bernards, Jan H M Schellens, Sofie Wilgenhof
A Proof-of-Concept Study of Sequential Treatment with the HDAC Inhibitor Vorinostat following BRAF and MEK Inhibitors in BRAFV600-Mutated Melanoma. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (15) (2024)
Marinda Meertens, Eline L Giraud, Maud B A van der Kleij, Kim Westerdijk, Niels A D Guchelaar, Roos F Bleckman, Amy Rieborn, Alex L T Imholz, Hans-Martin Otten, Annelie Vulink, Maartje Los, Paul Hamberg, Winette T A van der Graaf, Hans Gelderblom, Dirk Jan A R Moes, K Esther Broekman, Daan J Touw, Stijn L W Koolen, Ron H J Mathijssen, Alwin D R Huitema, Nielka P van Erp, Ingrid M E Desar, Neeltje Steeghs, null null
Evaluating the Clinical Impact and Feasibility of Therapeutic Drug Monitoring of Pazopanib in a Real-World Soft-Tissue Sarcoma Cohort. Clinical pharmacokinetics 63 (7) (2024)
Niels A D Guchelaar, Maud B A van der Kleij, Neeltje Steeghs, Alwin D R Huitema, Ron H J Mathijssen, Stijn L W Koolen
Therapeutic Drug Monitoring of Oral Oncology Drugs: Finding the Right Nails. Clinical pharmacology and therapeutics (2024)
Michael C Heinrich, Robin L Jones, Suzanne George, André B P van Kuilenburg, Patrick Schöffski, Margaret von Mehren, John R Zalcberg, Yoon-Koo Kang, Albiruni Abdul Razak, Jonathan Trent, Steven Attia, Axel Le Cesne, Brittany L Siontis, David Goldstein, Kjetil Boye, Cesar Sanchez, Neeltje Steeghs, Piotr Rutkowski, Mihaela Druta, Cesar Serrano, Neeta Somaiah, Ping Chi, William Reichmann, Kam Sprott, Haroun Achour, Matthew L Sherman, Rodrigo Ruiz-Soto, Jean Yves Blay, Sebastian Bauer
Ripretinib versus sunitinib in gastrointestinal stromal tumor: ctDNA biomarker analysis of the phase 3 INTRIGUE trial. Nature medicine 30 (2) (2024)
Neeltje Steeghs, Carlos Alberto Gomez Roca, Kristoffer Staal Rohrberg, Morten Mau Sorensen, Debbie G J Robbrecht, Josep Tabernero, Samreen Ahmed, Maria E Rodríguez-Ruiz, Caroline Ardeshir, Daniela Schmid, Nassim Sleiman, Carl Watson, Hanna Piper-Lepoutre, David Dejardin, Stefan Evers, Christophe Boetsch, Jehad Charo, Volker Teichgräber, Ignacio Melero Bermejo
Safety, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity from a Phase I Study of Simlukafusp Alfa (FAP-IL2v) in Advanced/Metastatic Solid Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (13) (2024)
Deborah van de Wal, Dide den Hollander, Ingrid M E Desar, André B P van Kuilenburg, Astrid W Oosten, Anna K L Reyners, Neeltje Steeghs, Olga Husson, Winette T A van der Graaf
Financial difficulties experienced by patients with gastrointestinal stromal tumours (GIST) in the Netherlands: data from a cross-sectional multicentre study. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 32 (5) (2024)
Neil H Segal, Ignacio Melero Bermejo, Victor Moreno, Neeltje Steeghs, Aurélien Marabelle, Kristoffer Staal Rohrberg, Maria E Rodriguez-Ruiz, Joseph P Eder, Cathy Eng, Gulam A Manji, Daniel Waterkamp, Barbara Leutgeb, Said Bouseida, Nick Flinn, Meghna Das Thakur, Markus C Elze, Hartmut Koeppen, Candice Jamois, Meret Martin-Facklam, Christopher H Lieu, Emiliano Calvo, Luis Paz-Ares, Josep Tabernero, Guillem Argilés
CEA-CD3 bispecific antibody cibisatamab with or without atezolizumab in patients with CEA-positive solid tumours: results of two multi-institutional Phase 1 trials. Nature communications 15 (1) (2024)
Michael C Heinrich, Robin L Jones, Suzanne George, André B P van Kuilenburg, Patrick Schöffski, Margaret von Mehren, John R Zalcberg, Yoon-Koo Kang, Albiruni Abdul Razak, Jonathan Trent, Steven Attia, Axel Le Cesne, Brittany L Siontis, David Goldstein, Kjetil Boye, Cesar Sanchez, Neeltje Steeghs, Piotr Rutkowski, Mihaela Druta, Cesar Serrano, Neeta Somaiah, Ping Chi, William Reichmann, Kam Sprott, Haroun Achour, Matthew L Sherman, Rodrigo Ruiz-Soto, Jean Yves Blay, Sebastian Bauer
Ripretinib versus sunitinib in gastrointestinal stromal tumor: ctDNA biomarker analysis of the phase 3 INTRIGUE trial. Nature medicine 30 (2) (2024)
Cedric Lau, Ma Ida Mohmaed Ali, Lishi Lin, Dorieke E M van Balen, Bart A W Jacobs, Bastiaan Nuijen, Robert M Smeenk, Neeltje Steeghs, Alwin D R Huitema
Impact of bariatric surgery on oral anticancer drugs: an analysis of real-world data. Cancer chemotherapy and pharmacology 94 (1) (2024)
Neil H Segal, Ignacio Melero Bermejo, Victor Moreno, Neeltje Steeghs, Aurélien Marabelle, Kristoffer Staal Rohrberg, Maria E Rodriguez-Ruiz, Joseph P Eder, Cathy Eng, Gulam A Manji, Daniel Waterkamp, Barbara Leutgeb, Said Bouseida, Nick Flinn, Meghna Das Thakur, Markus C Elze, Hartmut Koeppen, Candice Jamois, Meret Martin-Facklam, Christopher H Lieu, Emiliano Calvo, Luis Paz-Ares, Josep Tabernero, Guillem Argilés
CEA-CD3 bispecific antibody cibisatamab with or without atezolizumab in patients with CEA-positive solid tumours: results of two multi-institutional Phase 1 trials. Nature communications 15 (1) (2024)
Niels A D Guchelaar, Maud B A van der Kleij, Neeltje Steeghs, Alwin D R Huitema, Ron H J Mathijssen, Stijn L W Koolen
Therapeutic Drug Monitoring of Oral Oncology Drugs: Finding the Right Nails. Clinical pharmacology and therapeutics 116 (3) (2024)
Maud B A van der Kleij, Niels A D Guchelaar, Marinda Meertens, Kim Westerdijk, Eline L Giraud, Roos F Bleckman, Stefanie L Groenland, Ruben A G van Eerden, Alex L T Imholz, Annelie J E Vulink, Hans-Martin Otten, Helle-Brit Fiebrich-Westra, Floor J E Lubberman, Ingrid M E Desar, Dirk Jan A R Moes, Daan J Touw, Stijn L W Koolen, Hans Gelderblom, Anna K L Reyners, Nielka P van Erp, Ron H J Mathijssen, Alwin D R Huitema, null null, Neeltje Steeghs
Reasons for non-feasibility of therapeutic drug monitoring of oral targeted therapies in oncology - an analysis of the closed cohorts of a multicentre prospective study. British journal of cancer 131 (5) (2024)
Neeltje Steeghs, Carlos Alberto Gomez Roca, Kristoffer Staal Rohrberg, Morten Mau Sorensen, Debbie G J Robbrecht, Josep Tabernero, Samreen Ahmed, Maria E Rodríguez-Ruiz, Caroline Ardeshir, Daniela Schmid, Nassim Sleiman, Carl Watson, Hanna Piper-Lepoutre, David Dejardin, Stefan Evers, Christophe Boetsch, Jehad Charo, Volker Teichgräber, Ignacio Melero Bermejo
Safety, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity from a Phase I Study of Simlukafusp Alfa (FAP-IL2v) in Advanced/Metastatic Solid Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (13) (2024)
Cedric Lau, Ma Ida Mohmaed Ali, Lishi Lin, Dorieke E M van Balen, Bart A W Jacobs, Bastiaan Nuijen, Robert M Smeenk, Neeltje Steeghs, Alwin D R Huitema
Impact of bariatric surgery on oral anticancer drugs: an analysis of real-world data. Cancer chemotherapy and pharmacology (2024)
Marinda Meertens, Eline L Giraud, Maud B A van der Kleij, Kim Westerdijk, Niels A D Guchelaar, Roos F Bleckman, Amy Rieborn, Alex L T Imholz, Hans-Martin Otten, Annelie Vulink, Maartje Los, Paul Hamberg, Winette T A van der Graaf, Hans Gelderblom, Dirk Jan A R Moes, K Esther Broekman, Daan J Touw, Stijn L W Koolen, Ron H J Mathijssen, Alwin D R Huitema, Nielka P van Erp, Ingrid M E Desar, Neeltje Steeghs, null null
Evaluating the Clinical Impact and Feasibility of Therapeutic Drug Monitoring of Pazopanib in a Real-World Soft-Tissue Sarcoma Cohort. Clinical pharmacokinetics 63 (7) (2024)
Neil H Segal, Ignacio Melero Bermejo, Victor Moreno, Neeltje Steeghs, Aurélien Marabelle, Kristoffer Staal Rohrberg, Maria E Rodriguez-Ruiz, Joseph P Eder, Cathy Eng, Gulam A Manji, Daniel Waterkamp, Barbara Leutgeb, Said Bouseida, Nick Flinn, Meghna Das Thakur, Markus C Elze, Hartmut Koeppen, Candice Jamois, Meret Martin-Facklam, Christopher H Lieu, Emiliano Calvo, Luis Paz-Ares, Josep Tabernero, Guillem Argilés
CEA-CD3 bispecific antibody cibisatamab with or without atezolizumab in patients with CEA-positive solid tumours: results of two multi-institutional Phase 1 trials. Nature communications 15 (1) (2024)
Deborah van de Wal, Dide den Hollander, Ingrid M E Desar, André B P van Kuilenburg, Astrid W Oosten, Anna K L Reyners, Neeltje Steeghs, Olga Husson, Winette T A van der Graaf
Financial difficulties experienced by patients with gastrointestinal stromal tumours (GIST) in the Netherlands: data from a cross-sectional multicentre study. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 32 (5) (2024)
Deborah van de Wal, Dide den Hollander, Ingrid M E Desar, André B P van Kuilenburg, Astrid W Oosten, Anna K L Reyners, Neeltje Steeghs, Olga Husson, Winette T A van der Graaf
Financial difficulties experienced by patients with gastrointestinal stromal tumours (GIST) in the Netherlands: data from a cross-sectional multicentre study. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 32 (5) (2024)
Deborah van de Wal, Dide den Hollander, Ingrid M E Desar, André B P van Kuilenburg, Astrid W Oosten, Anna K L Reyners, Neeltje Steeghs, Olga Husson, Winette T A van der Graaf
Financial difficulties experienced by patients with gastrointestinal stromal tumours (GIST) in the Netherlands: data from a cross-sectional multicentre study. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 32 (5) (2024)
Javier Carmona, Elena Chavarria, Kate Donoghue, Christina von Gertten, Petra Oberrauch, Emma Pailler, Giovanni Scoazec, Ruud Weijer, Judith Balmaña, Irene Brana, Cinzia Brunelli, Suzette Delaloge, Marc Deloger, Pierre Delpy, Ingemar Ernberg, Rebecca C Fitzgerald, Elena Garralda, Martin Lablans, Janne Lehtiö, Carlos Lopez, Maialen Fernández, Rosalba Miceli, Paolo G Nuciforo, Raquel Perez-Lopez, Elena Provenzano, Marjanka K Schmidt, Cesar Serrano, Neeltje Steeghs, David Tamborero, Valtteri Wirta, Richard D Baird, Karen Barker, Fabrice Barlesi, Michael Baumann, Jonas Bergh, Filippo G De Braud, Karim Fizazi, Stefan Fröhling, Alejandro Piris-Giménez, Kenneth Seamon, Michiel S Van Der Heijden, Wilbert Zwart, Josep Tabernero
Cancer Core Europe: Leveraging Institutional Synergies to Advance Oncology Research and Care Globally. Cancer discovery 14 (7) (2024)
Deborah van de Wal, Dide den Hollander, Ingrid M E Desar, André B P van Kuilenburg, Astrid W Oosten, Anna K L Reyners, Neeltje Steeghs, Olga Husson, Winette T A van der Graaf
Financial difficulties experienced by patients with gastrointestinal stromal tumours (GIST) in the Netherlands: data from a cross-sectional multicentre study. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 32 (5) (2024)
Michael C Heinrich, Robin L Jones, Suzanne George, André B P van Kuilenburg, Patrick Schöffski, Margaret von Mehren, John R Zalcberg, Yoon-Koo Kang, Albiruni Abdul Razak, Jonathan Trent, Steven Attia, Axel Le Cesne, Brittany L Siontis, David Goldstein, Kjetil Boye, Cesar Sanchez, Neeltje Steeghs, Piotr Rutkowski, Mihaela Druta, Cesar Serrano, Neeta Somaiah, Ping Chi, William Reichmann, Kam Sprott, Haroun Achour, Matthew L Sherman, Rodrigo Ruiz-Soto, Jean Yves Blay, Sebastian Bauer
Ripretinib versus sunitinib in gastrointestinal stromal tumor: ctDNA biomarker analysis of the phase 3 INTRIGUE trial. Nature medicine 30 (2) (2024)
Alaa Embaby, Sanne C F A Huijberts, Liqin Wang, Rodrigo Leite de Oliveira, Hilde Rosing, Bastiaan Nuijen, Joyce Sanders, Ingrid Hofland, Charlaine van Steenis, Roelof J C Kluin, Cor Lieftink, Christopher G Smith, Christian U Blank, Johannes V van Thienen, John B A G Haanen, Neeltje Steeghs, Frans L Opdam, Jos H Beijnen, Alwin D R Huitema, René Bernards, Jan H M Schellens, Sofie Wilgenhof
A proof-of-concept study of sequential treatment with the HDAC inhibitor vorinostat following BRAF and MEK inhibitors in BRAFV600mutated melanoma. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Michael C Heinrich, Robin L Jones, Suzanne George, André B P van Kuilenburg, Patrick Schöffski, Margaret von Mehren, John R Zalcberg, Yoon-Koo Kang, Albiruni Abdul Razak, Jonathan Trent, Steven Attia, Axel Le Cesne, Brittany L Siontis, David Goldstein, Kjetil Boye, Cesar Sanchez, Neeltje Steeghs, Piotr Rutkowski, Mihaela Druta, Cesar Serrano, Neeta Somaiah, Ping Chi, William Reichmann, Kam Sprott, Haroun Achour, Matthew L Sherman, Rodrigo Ruiz-Soto, Jean Yves Blay, Sebastian Bauer
Ripretinib versus sunitinib in gastrointestinal stromal tumor: ctDNA biomarker analysis of the phase 3 INTRIGUE trial. Nature medicine 30 (2) (2024)
Neil H Segal, Ignacio Melero Bermejo, Victor Moreno, Neeltje Steeghs, Aurélien Marabelle, Kristoffer Staal Rohrberg, Maria E Rodriguez-Ruiz, Joseph P Eder, Cathy Eng, Gulam A Manji, Daniel Waterkamp, Barbara Leutgeb, Said Bouseida, Nick Flinn, Meghna Das Thakur, Markus C Elze, Hartmut Koeppen, Candice Jamois, Meret Martin-Facklam, Christopher H Lieu, Emiliano Calvo, Luis Paz-Ares, Josep Tabernero, Guillem Argilés
CEA-CD3 bispecific antibody cibisatamab with or without atezolizumab in patients with CEA-positive solid tumours: results of two multi-institutional Phase 1 trials. Nature communications 15 (1) (2024)
Michael C Heinrich, Robin L Jones, Suzanne George, André B P van Kuilenburg, Patrick Schöffski, Margaret von Mehren, John R Zalcberg, Yoon-Koo Kang, Albiruni Abdul Razak, Jonathan Trent, Steven Attia, Axel Le Cesne, Brittany L Siontis, David Goldstein, Kjetil Boye, Cesar Sanchez, Neeltje Steeghs, Piotr Rutkowski, Mihaela Druta, Cesar Serrano, Neeta Somaiah, Ping Chi, William Reichmann, Kam Sprott, Haroun Achour, Matthew L Sherman, Rodrigo Ruiz-Soto, Jean Yves Blay, Sebastian Bauer
Ripretinib versus sunitinib in gastrointestinal stromal tumor: ctDNA biomarker analysis of the phase 3 INTRIGUE trial. Nature medicine 30 (2) (2024)
Cedric Lau, Ma Ida Mohmaed Ali, Lishi Lin, Dorieke E M van Balen, Bart A W Jacobs, Bastiaan Nuijen, Robert M Smeenk, Neeltje Steeghs, Alwin D R Huitema
Impact of bariatric surgery on oral anticancer drugs: an analysis of real-world data. Cancer chemotherapy and pharmacology 94 (1) (2024)
Cedric Lau, Ma Ida Mohmaed Ali, Lishi Lin, Dorieke E M van Balen, Bart A W Jacobs, Bastiaan Nuijen, Robert M Smeenk, Neeltje Steeghs, Alwin D R Huitema
Impact of bariatric surgery on oral anticancer drugs: an analysis of real-world data. Cancer chemotherapy and pharmacology 94 (1) (2024)
Maud B A van der Kleij, Niels A D Guchelaar, Marinda Meertens, Kim Westerdijk, Eline L Giraud, Roos F Bleckman, Stefanie L Groenland, Ruben A G van Eerden, Alex L T Imholz, Annelie J E Vulink, Hans-Martin Otten, Helle-Brit Fiebrich-Westra, Floor J E Lubberman, Ingrid M E Desar, Dirk Jan A R Moes, Daan J Touw, Stijn L W Koolen, Hans Gelderblom, Anna K L Reyners, Nielka P van Erp, Ron H J Mathijssen, Alwin D R Huitema, null null, Neeltje Steeghs
Reasons for non-feasibility of therapeutic drug monitoring of oral targeted therapies in oncology - an analysis of the closed cohorts of a multicentre prospective study. British journal of cancer (2024)
Neeltje Steeghs, Carlos Alberto Gomez Roca, Kristoffer Staal Rohrberg, Morten Mau Sorensen, Debbie G J Robbrecht, Josep Tabernero, Samreen Ahmed, Maria E Rodríguez-Ruiz, Caroline Ardeshir, Daniela Schmid, Nassim Sleiman, Carl Watson, Hanna Piper-Lepoutre, David Dejardin, Stefan Evers, Christophe Boetsch, Jehad Charo, Volker Teichgräber, Ignacio Melero Bermejo
Safety, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity from a Phase I Study of Simlukafusp Alfa (FAP-IL2v) in Advanced/Metastatic Solid Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (13) (2024)
Michael C Heinrich, Robin L Jones, Suzanne George, André B P van Kuilenburg, Patrick Schöffski, Margaret von Mehren, John R Zalcberg, Yoon-Koo Kang, Albiruni Abdul Razak, Jonathan Trent, Steven Attia, Axel Le Cesne, Brittany L Siontis, David Goldstein, Kjetil Boye, Cesar Sanchez, Neeltje Steeghs, Piotr Rutkowski, Mihaela Druta, Cesar Serrano, Neeta Somaiah, Ping Chi, William Reichmann, Kam Sprott, Haroun Achour, Matthew L Sherman, Rodrigo Ruiz-Soto, Jean Yves Blay, Sebastian Bauer
Ripretinib versus sunitinib in gastrointestinal stromal tumor: ctDNA biomarker analysis of the phase 3 INTRIGUE trial. Nature medicine (2024)
Javier Carmona, Elena Chavarria, Kate Donoghue, Christina von Gertten, Petra Oberrauch, Emma Pailler, Giovanni Scoazec, Ruud Weijer, Judith Balmaña, Irene Brana, Cinzia Brunelli, Suzette Delaloge, Marc Deloger, Pierre Delpy, Ingemar Ernberg, Rebecca C Fitzgerald, Elena Garralda, Martin Lablans, Janne Lehtiö, Carlos Lopez, Maialen Fernández, Rosalba Miceli, Paolo G Nuciforo, Raquel Perez-Lopez, Elena Provenzano, Marjanka K Schmidt, Cesar Serrano, Neeltje Steeghs, David Tamborero, Valtteri Wirta, Richard D Baird, Karen Barker, Fabrice Barlesi, Michael Baumann, Jonas Bergh, Filippo G De Braud, Karim Fizazi, Stefan Fröhling, Alejandro Piris-Giménez, Kenneth Seamon, Michiel S Van Der Heijden, Wilbert Zwart, Josep Tabernero
Cancer Core Europe: Leveraging Institutional Synergies to Advance Oncology Research and Care Globally. Cancer discovery (2024)
Deborah van de Wal, Dide den Hollander, Ingrid M E Desar, André B P van Kuilenburg, Astrid W Oosten, Anna K L Reyners, Neeltje Steeghs, Olga Husson, Winette T A van der Graaf
Financial difficulties experienced by patients with gastrointestinal stromal tumours (GIST) in the Netherlands: data from a cross-sectional multicentre study. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 32 (5) (2024)
Marinda Meertens, Eline L Giraud, Maud B A van der Kleij, Kim Westerdijk, Niels A D Guchelaar, Roos F Bleckman, Amy Rieborn, Alex L T Imholz, Hans-Martin Otten, Annelie Vulink, Maartje Los, Paul Hamberg, Winette T A van der Graaf, Hans Gelderblom, Dirk Jan A R Moes, K Esther Broekman, Daan J Touw, Stijn L W Koolen, Ron H J Mathijssen, Alwin D R Huitema, Nielka P van Erp, Ingrid M E Desar, Neeltje Steeghs, null null
Evaluating the Clinical Impact and Feasibility of Therapeutic Drug Monitoring of Pazopanib in a Real-World Soft-Tissue Sarcoma Cohort. Clinical pharmacokinetics (2024)
Neeltje Steeghs, Carlos Alberto Gomez Roca, Kristoffer Staal Rohrberg, Morten Mau Sorensen, Debbie G J Robbrecht, Josep Tabernero, Samreen Ahmed, Maria E Rodríguez-Ruiz, Caroline Ardeshir, Daniela Schmid, Nassim Sleiman, Carl Watson, Hanna Piper-Lepoutre, David Dejardin, Stefan Evers, Christophe Boetsch, Jehad Charo, Volker Teichgräber, Ignacio Melero Bermejo
Safety, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity from a Phase I Study of Simlukafusp Alfa (FAP-IL2v) in Advanced/Metastatic Solid Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Luis G Paz-Ares, Stephane Champiat, W Victoria Lai, Hiroki Izumi, Ramaswamy Govindan, Michael J Boyer, Horst-Dieter Hummel, Hossein Borghaei, Melissa Lynne Johnson, Neeltje Steeghs, Fiona Blackhall, Afshin Dowlati, Noemí Reguart, Tatsuya Yoshida, Kai He, Shirish M Gadgeel, Enriqueta Felip Font, Yiran Zhang, Amrita Pati, Mukul Minocha, Sujoy Mukherjee, Amanda Goldrick, Dirk Nagorsen, Nooshin Hashemi Sadraei, Taofeek Kunle Owonikoko
Tarlatamab, a First-In-Class DLL3-Targeted Bispecific T-Cell Engager, in Recurrent Small Cell Lung Cancer: An Open-Label, Phase I Study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2023)
Jason van Leuven, Simon Evans, Ganessan Kichenadasse, Neeltje Steeghs, Billie Bonevski, Gerd Mikus, Madelé van Dyk
Framework for Implementing Individualised Dosing of Anti-Cancer Drugs in Routine Care: Overcoming the Logistical Challenges. Cancers 15 (13) (2023)
Maud B A van der Kleij, Niels A D Guchelaar, Ron H J Mathijssen, Jurjen Versluis, Alwin D R Huitema, Stijn L W Koolen, Neeltje Steeghs
Therapeutic Drug Monitoring of Kinase Inhibitors in Oncology. Clinical pharmacokinetics (2023)
Luis G Paz-Ares, Stephane Champiat, W Victoria Lai, Hiroki Izumi, Ramaswamy Govindan, Michael J Boyer, Horst-Dieter Hummel, Hossein Borghaei, Melissa Lynne Johnson, Neeltje Steeghs, Fiona Blackhall, Afshin Dowlati, Noemí Reguart, Tatsuya Yoshida, Kai He, Shirish M Gadgeel, Enriqueta Felip Font, Yiran Zhang, Amrita Pati, Mukul Minocha, Sujoy Mukherjee, Amanda Goldrick, Dirk Nagorsen, Nooshin Hashemi Sadraei, Taofeek Kunle Owonikoko
Tarlatamab, a first-in-class DLL3-targeted bispecific T cell engager, in recurrent small-cell lung cancer: an open-label, phase 1 study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2023)
Yvette Drew, Jae-Weon Kim, Richard T Penson, David M O'Malley, Christine Parkinson, Patricia Roxburgh, Ruth Plummer, Seock-Ah Im, Martina Imbimbo, Michelle Ferguson, Ora Rosengarten, Neeltje Steeghs, Min Hwan Kim, Einav Nili Gal-Yam, Daliah Tsoref, Jae-Hoon Kim, Benoit You, Maja J A de Jonge, Roy I Lalisang, Eelke H Gort, Sara Bastian, Kassondra Meyer, Laura Feeney, Nigel Baker, Mei-Lin Ah-See, Susan M Domchek, Susana Banerjee
Olaparib plus Durvalumab, with or without Bevacizumab, as Treatment in PARP Inhibitor-Naïve Platinum-Sensitive Relapsed Ovarian Cancer: A Phase II Multi-Cohort Study. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Lindsay Angus, Marcel Smid, Saskia M Wilting, Manouk K Bos, Neeltje Steeghs, Inge R H M Konings, Vivianne C G Tjan-Heijnen, Johanna M G H van Riel, Agnes J van de Wouw, null Cpct Consortium, Edwin Cuppen, Martijn Paul Lolkema, Agnes Jager, Stefan Sleijfer, John W M Martens
Genomic Alterations Associated with Estrogen Receptor Pathway Activity in Metastatic Breast Cancer Have a Differential Impact on Downstream ER Signaling. Cancers 15 (17) (2023)
Benedito Arruda Carneiro, Ludimila Cavalcante, Devalingam Mahalingam, Anwaar Saeed, Howard Safran, Wen Wee Ma, Andrew L Coveler, Steven Francis Powell, Bruno R Bastos, Elizabeth J Davis, Vaibhav Sahai, William Mikrut, James Longstreth, Sheri Smith, Taylor M Weiskittel, Hu Li, Brittany A Borden, Robert Donald Harvey, Solmaz Sahebjam, Andres Cervantes, Austin Koukol, Andrew P Mazar, Neeltje Steeghs, Razelle Kurzrock, Francis J Giles, Pamela N Munster
Phase 1 study of Elraglusib (9-ING-41), a glycogen synthase kinase-3b inhibitor, as monotherapy or combined with chemotherapy in patients with advanced malignancies. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Anne Dirkson, Dide den Hollander, Suzan Verberne, Ingrid M E Desar, Olga Husson, Winette T A van der Graaf, Astrid W Oosten, Anna K L Reyners, Neeltje Steeghs, Wouter van Loon, Gerard van Oortmerssen, André B P van Kuilenburg, Wessel Kraaij
Sample Bias in Web-Based Patient-Generated Health Data of Dutch Patients With Gastrointestinal Stromal Tumor: Survey Study. JMIR formative research 6 (12) (2022)
Deborah van de Wal, Mai Elie, Axel Le Cesne, Elena Fumagalli, Dide den Hollander, Robin L Jones, Gloria Marquina, Neeltje Steeghs, Winette T A van der Graaf, Olga Husson
Health-Related Quality of Life and Side Effects in Gastrointestinal Stromal Tumor (GIST) Patients Treated with Tyrosine Kinase Inhibitors: A Systematic Review of the Literature. Cancers 14 (7) (2022)
Funda Meric-Bernstam, Randy F Sweis, Stefan Kasper, Omid Hamid, Shailender Bhatia, Reinhard Dummer, Agostina Stradella, Georgina V Long, Anna Spreafico, Toshio Shimizu, Neeltje Steeghs, Jason John Luke, Sarah M McWhirter, Thomas Müller, Nitya Nair, Nancy Lewis, Xinhui Chen, Andrew Bean, Lisa M Kattenhorn, Marc R Pelletier, Shahneen Sandhu
Combination of the STING Agonist MIW815 and PD-1 Inhibitor Spartalizumab in Advanced/Metastatic Solid Tumors or Lymphomas: An Open-label, Multicenter, Phase Ib Study. Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
Anne Dirkson, Dide den Hollander, Suzan Verberne, Ingrid M E Desar, Olga Husson, Winette T A van der Graaf, Astrid W Oosten, Anna K L Reyners, Neeltje Steeghs, Wouter van Loon, Gerard van Oortmerssen, André B P van Kuilenburg, Wessel Kraaij
Sample Bias in Web-Based Patient-Generated Health Data of Dutch Patients With Gastrointestinal Stromal Tumor: Survey Study. JMIR formative research 6 (12) (2022)
Anne Dirkson, Dide den Hollander, Suzan Verberne, Ingrid M E Desar, Olga Husson, Winette T A van der Graaf, Astrid W Oosten, Anna K L Reyners, Neeltje Steeghs, Wouter van Loon, Gerard van Oortmerssen, André B P van Kuilenburg, Wessel Kraaij
Sample Bias in Web-Based Patient-Generated Health Data of Dutch Patients With Gastrointestinal Stromal Tumor: Survey Study. JMIR formative research 6 (12) (2022)
Anne Dirkson, Dide den Hollander, Suzan Verberne, Ingrid M E Desar, Olga Husson, Winette T A van der Graaf, Astrid W Oosten, Anna K L Reyners, Neeltje Steeghs, Wouter van Loon, Gerard van Oortmerssen, André B P van Kuilenburg, Wessel Kraaij
Sample Bias in Web-Based Patient-Generated Health Data of Dutch Patients With Gastrointestinal Stromal Tumor: Survey Study. JMIR formative research 6 (12) (2022)
Laura Molenaar-Kuijsten, Milan van Meekeren, Remy B Verheijen, Judith V M G Bovée, Marta Fiocco, Bas Thijssen, Hilde Rosing, Alwin D R Huitema, Aisha B Miah, André B P van Kuilenburg, Rick L M Haas, Neeltje Steeghs
Intra-Tumoral Pharmacokinetics of Pazopanib in Combination with Radiotherapy in Patients with Non-Metastatic Soft-Tissue Sarcoma. Cancers 13 (22) (2021)
Anna M Mc Laughlin, Eduard Schmulenson, Olga Teplytska, Sebastian Zimmermann, Patrick Opitz, Stefanie L Groenland, Alwin D R Huitema, Neeltje Steeghs, Lothar Müller, Stefan Fuxius, Gerald Illerhaus, Markus Joerger, Frank Mayer, Uwe Fuhr, Stefan Holdenrieder, Georg Hempel, Oliver Scherf-Clavel, Ulrich Jaehde, Charlotte Kloft, null For The On-Target Study Consortium
Developing a Nationwide Infrastructure for Therapeutic Drug Monitoring of Targeted Oral Anticancer Drugs: The ON-TARGET Study Protocol. Cancers 13 (24) (2021)
Begoña de Las Heras, Dalila Bouyoucef-Cherchalli, Lesley Reeve, Andreas Reichl, Debra Mandarino, Stephen Flach, Laura Vidal, Emilie M J van Brummelen, Neeltje Steeghs
Healthy volunteers in first-in-human oncology drug development for small molecules. British journal of clinical pharmacology (2021)
Jip M van Elst, Nikki S IJzerman, Ron H J Mathijssen, Neeltje Steeghs, Anna K L Reyners, Jacco-Juri de Haan
Taste, smell and mouthfeel disturbances in patients with gastrointestinal stromal tumors treated with tyrosine-kinase inhibitors. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer (2021)
Michiel C Verboom, André B P van Kuilenburg, J Martijn Kerst, Neeltje Steeghs, Anna K L Reyners, Stefan Sleijfer, Winette T A van der Graaf, Wilbert B van den Hout
Survival and Cost-Effectiveness of Trabectedin Compared to Ifosfamide Monotherapy in Advanced Soft Tissue Sarcoma Patients. Sarcoma 2019 (2019)
Danique L M van Broekhoven, Arie Jan Verschoor, Thijs van Dalen, Dirk J Grünhagen, Michael A den Bakker, André B P van Kuilenburg, Judith V M G Bovee, Rick L M Haas, Han J Bonenkamp, Frits van Coevorden, Diederik Ten Oever, Winette T A van der Graaf, Uta E Flucke, Elisabeth Pras, Anna K L Reyners, Anneke M Westermann, Foppe Oldenburger, Cornelis Verhoef, Neeltje Steeghs
Outcome of Nonsurgical Management of Extra-Abdominal, Trunk, and Abdominal Wall Desmoid-Type Fibromatosis: A Population-Based Study in the Netherlands. Sarcoma 2018 (2018)