Congenital Heart Disease: Growth Evaluation and Sport Activity in a Paediatric Population.
Thomas ZollerMaria Antonia PrioliMaria ClementeMara PilatiCamilla SandriniGiovanni Battista LucianiMarco Deganello SaccomaniBenjamim FicialMarcella GaffuriGiorgio PiacentiniLucia CalcianoAngelo PietrobelliPublished in: Children (Basel, Switzerland) (2022)
(1) Objective: To evaluate: (i) the associations of age and disease severity with anthropometric indices and weight status, (ii) the difference in the frequency of sports activity among different levels of disease severity in paediatric patients with congenital heart disease (CHD). (2) Methods: Clinical data of Caucasian children (aged 2-18 years) diagnosed with CHD (2005-2018) were retrospectively collected from the electronic register of outpatient visits. Of the 475 children with CHD, 368 children and their 1690 complete anthropometric measurements were eligible for inclusion in our analysis. (3) Results: Significant increase with age was observed for weight z-score [beta (95%CI): 0.03 (0.02, 0.05) for one-unit of age] and BMI z-score [0.06 (0.03, 0.08)] but not for height z-score. The probability of being underweight and overweight/obese increased and decreased with disease severity, respectively. The obesity probability of patients with mild CHD (0.06 [95%CI: 0.03, 0.08]) was not statistically distinguishable from that of patients with moderate CHD (0.03 [95%CI: 0.02, 0.05]), whereas it was lower in patients with severe CHD (0.004 [95%CI: 0.0, 0.009]). No obese patients with a univentricular heart defect were observed. Days spent in sport activities were equal to 1.9 [95%CI: 1.6, 2.2] days/week, 1.9 [1.5, 2.2], 1.4 [1.1, 1.7] and 0.7 [0.1, 1.3] in patients with mild, moderate, severe and univentricular CHD, respectively. (4) Conclusions: The risk of being overweight and obese should not be underestimated in paediatric patients diagnosed with CHD, especially in children with mild or moderate heart defects. It could be prevented or reduced by promoting a healthy lifestyle.
Keyphrases
- congenital heart disease
- weight loss
- body mass index
- young adults
- metabolic syndrome
- weight gain
- emergency department
- physical activity
- intensive care unit
- type diabetes
- bariatric surgery
- adipose tissue
- heart failure
- body composition
- ejection fraction
- insulin resistance
- randomized controlled trial
- clinical trial
- machine learning
- skeletal muscle
- prognostic factors
- study protocol
- electronic health record
- patient reported
- data analysis
- placebo controlled
- high school