Elevations in the Mitochondrial Matrix Protein Cyclophilin D Correlate With Reduced Parvalbumin Expression in the Prefrontal Cortex of Patients With Schizophrenia.
John T O'BrienSophia P JalilvandNeha A SujiRohan K JupellyAarron J PhensyJuliet M MwirigiHajira ElahiTheodore John PriceSven KroenerPublished in: Schizophrenia bulletin (2024)
Our findings support previously reported PVI anomalies in schizophrenia and suggest that CypD-mediated mPTP formation could be a potential contributor to PVI dysfunction in schizophrenia.