TYK2 promotes malignant peripheral nerve sheath tumor progression through inhibition of cell death.

Wenjing QinAbigail GodecXiaochun ZhangCuige ZhuJieya ShaoYu TaoXianzhang BuAngela C Hirbe

Published in: Cancer medicine (2019)

Taken together, these data illustrate the importance of TYK2 in MPNST pathogenesis and suggest that the TYK2 pathway may be a potential therapeutic target for these deadly cancers.

Keyphrases

peripheral nerve
cell death
poor prognosis
electronic health record
big data
young adults
human health
long non coding rna
cell proliferation
signaling pathway
data analysis