Two paralogous znf143 genes in zebrafish encode transcriptional activator proteins with similar functions but expressed at different levels during early development.

Published in: BMC molecular and cell biology (2020)

znf143a encodes a strong activator protein with high expression in neural tissues during early embryogenesis in zebrafish. Similar to its paralogous gene, znf143b, both znf143 genes are required for normal development in zebrafish.

Keyphrases

genome wide identification
genome wide
transcription factor
gene expression
nuclear factor
poor prognosis
genome wide analysis
binding protein
bioinformatics analysis
dna methylation
heat stress