Association study of human leukocyte antigen variants and idiopathic pulmonary fibrosis.
Beatriz Guillen-GuioMegan L PayntonRichard J AllenDaniel P W ChinLauren J DonoghueAmy StockwellOlivia C LeavyTamara Hernandez-BeeftinkCarl J ReynoldsPaul CullinanFernando MartinezHelen L BoothWilliam A FahyIan P HallSimon Paul HartMike R HillNik HiraniRichard B HubbardRobin J McAnultyAnn B MillarVidya NavaratnamEunice OballaHelen ParfreyGauri SainiIan SayersMartin D TobinMoira K B WhyteAyodeji AdegunsoyeNaftali KaminskiShwu-Fan MaMary E StrekYingze ZhangTasha E FingerlinMaria Molina-MolinaMargaret NeighborsX Rebecca ShengJustin M OldhamToby M MaherPhilip L MolyneauxCarlos FloresImre NothDavid A SchwartzBrian L YaspanR Gisli JenkinsLouise V WainEdward J HolloxPublished in: ERJ open research (2024)
Variation in the HLA region was not consistently associated with risk in studies of IPF. However, this does not preclude the possibility that other genomic regions linked to the immune response may be involved in the aetiology of IPF.