Exercise to preserve β-cell function in recent-onset Type 1 diabetes mellitus (EXTOD) - a randomized controlled pilot trial.
Parth NarendranN JacksonA DaleyD ThompsonK StokesS GreenfieldM CharltonM CurranT P J SolomonA NouwenS I LeeA R CooperM MostazirR S TaylorA KennedyR C AndrewsPublished in: Diabetic medicine : a journal of the British Diabetic Association (2017)
We show that it is possible to recruit and randomize people with newly diagnosed Type 1 diabetes to a trial of an exercise intervention, and increase and maintain their exercise levels for 12 months. Future trials need to incorporate measures of greater adherence to exercise training targets, and include more appropriate measures of β-cell function. (Clinical Trials Registry No; ISRCTN91388505).