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Modular signature of long non-coding RNA association networks as a prognostic biomarker in lung cancer.

Albert LiWen-Hsuan YuChia-Lang HsuHsuan-Cheng HuangHsueh-Fen Juan
Published in: BMC medical genomics (2021)
Taken together, we identified four novel LUAD prognosis-related lncRNA modules, and assessed the performance of the 4-modular lncRNA signature being a prognostic biomarker. Functionally speaking, these modules involve in oncogenic hallmarks as well as pathways. The results unveiled the co-regulated lncRNAs in LUAD and may provide a framework for further lncRNA studies in lung cancer.
Keyphrases
  • long non coding rna
  • poor prognosis
  • network analysis
  • transcription factor
  • case control
  • genome wide identification