Biological indicators of chemoresistance: an ex vivo analysis of γH2AX and p53 expression in feline injection-site sarcomas.
Yike BingZacharie WundTina AbratteLucia BorlleSusie KangTeresa SouthardKelly R HumePublished in: Cancer cell international (2018)
γH2AX expression, but not wild type p53, may potentially serve as a biomarker of resistance to platinum therapeutics in soft tissue sarcomas. To further investigate this finding, prospective, in vivo studies are indicated in animal models.