Methyl β-Cyclodextrin-sperm-mediated gene editing (MBCD-SMGE): a simple and efficient method for targeted mutant mouse production.

Parisa MoradbeigiSara HosseiniMohammad SalehiAsghar Mogheiseh

Published in: Biological procedures online (2024)

Overall, this study highlights the significant potential of the MBCD-SMGE technique for generating targeted mutant mice. It holds enormous promise for modeling human diseases and improving desirable traits in animals.

Keyphrases

wild type
cancer therapy
endothelial cells
big data
induced pluripotent stem cells
gene expression
type diabetes
ionic liquid
high fat diet induced
adipose tissue
pluripotent stem cells
machine learning
insulin resistance
artificial intelligence