Glucagon-like peptide-1 receptor agonists and the risk of atrial fibrillation in adults with diabetes: a real-world study.
Yunwen XuThomas A BoyleBeini LyuShoshana H BallewElizabeth SelvinAlexander R ChangLesley A InkerMorgan E GramsJung-Im ShinPublished in: Journal of general internal medicine (2024)
In this real-word study, GLP-1RA was associated with a lower risk of AF compared with DPP4i, but no difference compared with SGLT2i, suggesting that cardiovascular benefits of GLP-1RA use may extend to prevention for AF in patients with diabetes. Our findings call for future randomized controlled trials to focus on the effects of GLP-1RA on AF prevention.
Keyphrases
- skeletal muscle
- atrial fibrillation
- insulin resistance
- rheumatoid arthritis
- randomized controlled trial
- type diabetes
- disease activity
- cardiovascular disease
- heart failure
- ankylosing spondylitis
- oral anticoagulants
- left atrial
- clinical trial
- left atrial appendage
- adipose tissue
- systematic review
- systemic lupus erythematosus
- current status
- percutaneous coronary intervention
- direct oral anticoagulants
- acute coronary syndrome